Microscopy

MICRO MÉCANIQUE offers a comprehensive range of microscopy solutions, cameras, lenses, lighting, motorised stages, incubation chambers and accessories. We support you from selection to installation, including training and maintenance, to optimise your observations and protocols, from teaching laboratories to advanced research.

Electrophysiology & Neuroscience

For over 35 years, MICRO MÉCANIQUE SAS has been supporting researchers and laboratories in neuroscience, electrophysiology and optogenetics. We offer a comprehensive range of equipment (amplifiers, micromanipulators, microinjection systems, etc.) and comprehensive support: advice, installation, training and maintenance throughout France.

Integrated IPA/double IPA patch system

The IPA (one pre-amplifier) or Double IPA (two independent pre-amplifiers) system combines an integrated amplifier with an analogue/digital converter and SutterPatch software for data acquisition, management and analysis. The combination of two devices provides up to four head channels and 16 signals, including analogue inputs, analogue outputs and digital outputs. Data acquisition can be triggered by an on-board clock with microsecond resolution or an external TTL trigger. Imposed potential and impressed current can be switched automatically to avoid artefacts, with a holding potential of up to 1000 mV. The system is optimised for whole-cell recordings on tissue slices, adherent or dissociated cells. Data and analysis are visualised in 2D and 3D using the SutterPatch software, which also manages over 600 experimental metadata, covering biological parameters, instruments and applied stimuli. Additional modules enable synaptic event detection, action potential analysis and documentation of cell identity and status via camera. The optional front panel version facilitates I/O connections directly on the panel.

Integrated IPA/double IPA patch system features

  • Integrated patch-clamp amplifier with A/D and D/A converter
  • Versions available: IPA (1 preamplifier) or Double IPA (2 independent preamplifiers)
  • Two units can be combined for up to four head channels and 16 signals
  • 4 analogue input channels (±10 V)
  • 2 analogue output channels (±10 V)
  • 8 digital output channels (TTL)
  • Acquisition triggered by on-board clock or external TTL trigger
  • Single high-speed USB connection for acquisition and amplifier control
  • Automatic switching between impressed potential and impressed current to avoid artefacts
  • Holding potential up to 1000 mV
  • Optimised for whole cells on tissue slices, adherent or dissociated cells
  • 2D/3D data visualisation and analysis via SutterPatch® software
  • Optional modules: event detection, action potential analysis, camera for cell documentation
  • Recording and storage of over 600 experimental metadata

Dimensions and weight :

  • IPA: 48 × 30 × 4.5 cm / 4 kg
  • Double IPA: 48 × 30 × 9 cm / 3.7 kg
  • Front panel: 48 × 5 × 9 cm / 1.6 kg
  • Compatible with the majority of electrophysiology applications, including optogenetics and network studies

Documentation

Flyer

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