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    Microscopy

    MICRO MÉCANIQUE offers a comprehensive range of microscopy solutions, cameras, lenses, lighting, motorised stages, incubation chambers and accessories. We support you from selection to installation, including training and maintenance, to optimise your observations and protocols, from teaching laboratories to advanced research.

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    Electrophysiology & Neuroscience

    For over 35 years, MICRO MÉCANIQUE SAS has been supporting researchers and laboratories in neuroscience, electrophysiology and optogenetics. We offer a comprehensive range of equipment (amplifiers, micromanipulators, microinjection systems, etc.) and comprehensive support: advice, installation, training and maintenance throughout France.

    Axon Pclamp11 software

    The pClamp 11 software suite enables precise acquisition and analysis using impressed current or impressed potential techniques, for patch-clamp and intracellular experiments. It includes Clampex 11 for acquisition, AxoScope 11 for real-time visualisation, Clampfit 11 for data analysis and an optional advanced analysis module for sophisticated processing. This enhanced version offers a flexible protocol editor, the ability to view multiple channels simultaneously, and the creation of complex protocols including slots, ramps, cosine functions, sine or triangular profiles. The software is optimised for automatic detection of low-amplitude events, such as excitatory or inhibitory post-synaptic potentials, and includes numerous graphical and analytical tools for representing and interpreting electrophysiological data.

    Logiciel Axon Pclamp11
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    Axon Pclamp11 software features

    • Data acquisition and analysis in impressed current and impressed potential modes
    • Includes Clampex 11, AxoScope 11, Clampfit 11 and optional advanced analysis module
    • Flexible protocol editor with the ability to view multiple channels simultaneously
    • Creation of complex protocols: slots, ramps, cosine functions, two-phase pulse trains, sinusoidal or triangular profiles
    • Real-time analysis of amplitudes, areas, averages and standard deviations of events
    • Specialised analysis tools: FFT, variance-mean, per-event analysis, puff analysis, auto and cross correlation
    • Automatic detection of fast, low-amplitude events (EPSPs/IPSPs)
    • Analysis of open, closed and conductance states of ion channels
    • Advanced measurement of action potentials: amplitude, duration, rise/fall time, threshold and post-potentials
    • Management of up to eight levels of open states
    • Compatible with continuous or episodic data for complete channel analysis

    Documentation

    Brochure

    PDF file – 913.5 ko

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