Microscopy

MICRO MÉCANIQUE offers a comprehensive range of microscopy solutions, cameras, lenses, lighting, motorised stages, incubation chambers and accessories. We support you from selection to installation, including training and maintenance, to optimise your observations and protocols, from teaching laboratories to advanced research.

Electrophysiology & Neuroscience

For over 35 years, MICRO MÉCANIQUE SAS has been supporting researchers and laboratories in neuroscience, electrophysiology and optogenetics. We offer a comprehensive range of equipment (amplifiers, micromanipulators, microinjection systems, etc.) and comprehensive support: advice, installation, training and maintenance throughout France.

PiezoXpert® – Calibre Scientific

Calibre Scientific’s PiezoXpert® is a piezo-assisted micromanipulation system designed to facilitate penetration of cell membranes during microinjections.

Thanks to mechanical impulses transferred directly to the capillary without loss of intensity, the PiezoXpert® considerably improves experimental results, particularly in Piezo-ICSI-type procedures.

It integrates perfectly with Calibre Scientific manipulators and other standard systems, and is designed exclusively for research use.

Characteristics of PiezoXpert® – Calibre Scientific

  • Gentle and effective cell penetration for improved cell survival.
  • Piezo pulses transferred without loss of intensity to the capillary.
  • Use of a blunt microcapillary for optimal force transfer.
  • Significant reduction in oocyte deformation during ICSI.
  • Reproducible parameter setting with programmable keys.
  • Pulse triggering via ergonomic foot pedal or rotary knobs.
  • Clean” function for easy removal of external contaminants.
  • Visual feedback of triggered pulses on the interface.

Technical specifications of the PiezoXpert® – Calibre Scientific

Caractéristique Valeur
Method of operation Piezo assisted micromanipulation
Compatibility Calibre Scientific Systems
How it works High-frequency, low-amplitude mechanical pulses
Trigger Pedal or rotary knobs
Memorisable parameters Yes (programmable keys)
Clean function Yes, for capillary decontamination
Indication Research use only

Applications

  • Piezo-ICSI injection (mouse, horse, pig, etc.)
  • Transfer of embryonic stem cells or iPS into blastocysts or morulae
  • Enucleation and nuclear transfer
  • Blastomeric biopsy (mouse embryos)
  • Equine embryo biopsy for pre-implantation genetic testing
  • Injection of RNA/DNA into fertilised mammalian oocytes